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Program News and Releases
NYSTEM Releases Second Strategic Plan
ESSCB releases second Strategic Plan reviewing NYSTEM's accomplishments and setting forth objectives for the next phase of the program: "The New York State Stem Cell Science (NYSTEM) Program: A Report on Progress and a Vision for the Future."
ESSCB Full Board Meeting - May 17, 2016 - Webcast now available
We apologize for the poor quality of the webcast, a higher quality version can be streamed from the DOH website.
International Collaboration Produces Haploid Human Embryonic Stem Cells
An international collaboration between researchers in New York and Israel produces haploid human embryonic stem cells capable of normal differentiation.
Electrical Stimulation Provides Conditioning Cues for Generation of Mature Heart Muscle Cells from Human Pluripotent Stem Cells
Researchers led by Gordana Vunjak-Novakovic, the Mikati Foundation Professor of Biomedical Engineering and Medical Sciences at Columbia University, have for the first time demonstrated that electrical conditioning of stem cell-derived cardiomyocytes in three-dimensional culture promotes cardiomyocyte maturation. The therapeutic success of human stem cell-derived cardiomyocytes critically depends on their ability to respond to and integrate with the surrounding electromechanical environment. Dr. Vunjak-Novakovic’s team showed that cardiomyocytes adapt their autonomous beating rate to the frequency at which they were stimulated, an effect mediated by the emergence of a rapidly depolarizing cell population. This rate-adaptive behaviour is long-lasting and transferable to the surrounding cardiomyocytes. In summary, this exciting discovery sheds some light on more effective stem cell therapy of the heart by preconditioning human stem cell-derived cardiomyocytes with electrical stimulation.
Combination of Stem Cells and Gene Modifying Tools Provide Path to Vision Repair
Scientists led by Stephen Tsang and Vinit Mahajan used CRISPR/Cas9-based gene modification in patient-derived stem cells to repair a mutation that causes retinitis pigmentosa.
The Vascular Niche Controls Lung Repair
Bi-Sen Ding and Shahin Rafii explore the role of lung endothelial cells in response to damage.
Expert Panel Assesses NYSTEM Program
NYSTEM: Capitalizing on Opportunities and Confronting Challenges, a Report by the NYSTEM External Review Panel
Lorenz Studer Profiled in The Scientist
Dr. Lorenz Studer, M.D., of Memorial Sloan Kettering Cancer Center was recently profiled in The Scientist.
Improved Method to Convert Skin Cells to Dopamine Neurons
Jian Feng Publishes an Improved Method to Produce Dopamine Neurons From Patient Cells