John M. Canty, M.D.

Albert & Elizabeth Rekate Professor of Medicine
Chief, Division of Cardiovascular Medicine
State University of New York at Buffalo
canty@buffalo.edu

Dr. Canty heads the University's Center for Research in Cardiovascular Medicine. The center conducts translational research in patients with coronary artery disease as well as in animal models of chronic ischemic heart disease. The team is doing pioneering work investigating the mechanisms involved in sudden cardiac death, a condition caused by a catastrophic disruption in heart rhythm resulting in ventricular fibrillation. Other areas of investigational strength include the development of gene transfer and adult stem cell therapy treatments for ischemic heart disease and the implementation of high-throughput molecular biological approaches to identify mechanisms of acquired cardiovascular disease.

Select Publications

Suzuki, G., Iyer, V., Lee, T.C. and Canty, J.M. Jr. (2007).  Intracoronary injection of autologous mesenchymal stem cells (MSCs) increases the myocardial localization of CD133+ hematopoietic stem cells (HSCs) in swine with hybernating myocardium.  Circulation (Suppl 11): 11-133, 2007. 

Suzuki, G. Lee, T.C. Fallavollita, J.A. Canty, J.M., Jr. Adenoviral gene transfer of FGF-5 to hibernating myocardium improves function and stimulates myocytes to hypertrophy and reenter the cell cycle. Circulation Research; 2005; 96; 767-775.