Dr. Nikitin's laboratory focuses on understanding cancer pathogenesis with a particular attention to the role of stem cell compartment in carcinogenesis. This research includes addressing the questions of how tumor suppressor genes, microRNAs and microenvironmental factors regulate adult stem cells and how aberrations in those regulatory mechanisms may lead to cancer. These problems are studied in a number of established and newly generated genetically defined autochthonous mouse models of human breast, prostate and ovarian cancers.
Associate Professor of Pathology
Leader, Cornell Stem Cell Program